| | | | | | |
| M. Rossi | C | VAN | 10/20/2025 | Not playing | lower body | + |
| P. Laine | RW | MTL | 10/20/2025 | Won't play | lower body | + |
| K. Dach | C | MTL | 10/20/2025 | Unavailable | lower body | + |
| T. Bluege | C | VAN | 10/20/2025 | Unlikely to play | Undisclosed | + |
| P. Dubois | C | WSH | 10/20/2025 | Won't return | lower body | + |
| A. Romano | D | NYI | 10/20/2025 | Game-time call | Upper body | + |
| S. Noesen | C | NJ | 10/20/2025 | Nearing return to lineup | groin | + |
| E. Gudbra | D | CBJ | 10/21/2025 | Not playing | Upper body | + |
| L. O'Conn | RW | COL | 10/21/2025 | Still three weeks out from return | hip | + |
| H. Lindho | D | BOS | 10/21/2025 | Still seemingly battling injury | Undisclosed | + |
| C. Tanev | D | TOR | 10/21/2025 | Sustains upper-body injury | Upper body | + |
| M. Marchm | LW | CBJ | 10/21/2025 | Not playing | lower body | + |
| K. Dach | C | MTL | 10/21/2025 | Nearing return | lower body | + |
| A. Hill | G | VGK | 10/21/2025 | Injured in Monday's game | lower body | + |
| A. Romano | D | NYI | 10/21/2025 | Unavailable against San Jose | Upper body | + |
| J. Marche | LW | NSH | 10/21/2025 | Not suiting up against Anaheim | lower body | + |
| P. Laine | RW | MTL | 10/22/2025 | Seeking second opinion | lower body | + |
| M. Barron | LW | WIN | 10/22/2025 | Considered day-to-day | Undisclosed | + |
| A. Hill | G | VGK | 10/22/2025 | Considered week-to-week | lower body | + |
| B. Howden | C | VGK | 10/22/2025 | Trending toward playing | lower body | + |
| M. Kessel | D | BUF | 10/22/2025 | Could resume practicing soon | lower body | + |
| P. Engval | LW | NYI | 10/22/2025 | Likely out for season | ankle | + |
| C. Tanev | D | TOR | 10/22/2025 | Questionable for Friday's game | Upper body | + |
| A. Romano | D | NYI | 10/22/2025 | Not close to returning | Upper body | + |
| T. Bluege | C | VAN | 10/23/2025 | Missing another game | Undisclosed | + |
| H. Lindho | D | BOS | 10/23/2025 | Remains out | Undisclosed | + |
| J. Marche | LW | NSH | 10/23/2025 | Unavailable | lower body | + |
| H. Lindho | D | BOS | 10/23/2025 | Deemed game-time decision | Undisclosed | + |
| M. Marchm | LW | CBJ | 10/23/2025 | Considered game-time decision | lower body | + |
| D. Forbor | D | VAN | 10/24/2025 | Considered week-to-week | Undisclosed | + |
| A. Kerfoo | C | UTA | 10/24/2025 | Undergoes core muscle surgery | abdomen | + |
| J. Benn | C | DAL | 10/24/2025 | Begins skating | Upper body | + |
| S. Sabour | RW | TB | 10/24/2025 | Sent back to minors | Suspension | + |
| P. Dubois | C | WSH | 10/24/2025 | Not available | lower body | + |
| P. Laine | RW | MTL | 10/25/2025 | Out 3-4 months | abdomen | + |
| H. Lindho | D | BOS | 10/25/2025 | Unavailable | Undisclosed | + |
| J. Gadjov | LW | FLA | 10/27/2025 | Out at least one week | Upper body | + |
| M. Kessel | D | BUF | 10/27/2025 | Likely to return | lower body | + |
| B. Marcha | LW | FLA | 10/27/2025 | Unavailable | Personal | + |
| A. Romano | D | NYI | 10/27/2025 | Won't play | Upper body | + |
| C. Tanev | D | TOR | 10/27/2025 | Could return by end of week | Upper body | + |
| S. Mukham | D | SJ | 10/28/2025 | Classified as day-to-day | Upper body | + |
| E. Gudbra | D | CBJ | 10/28/2025 | out | hip | + |
| Z. Bogosi | D | MIN | 10/28/2025 | Not close to returning | lower body | + |
| C. Garlan | RW | VAN | 10/29/2025 | Not traveling with team | Undisclosed | + |
| E. Gudbra | D | CBJ | 10/29/2025 | Remains out for Wednesday's game | hip | + |
| C. Garlan | RW | VAN | 10/29/2025 | Departs Tuesday's game | Undisclosed | + |
| J. Harris | D | BOS | 10/30/2025 | Undergoes surgery | ankle | + |
| T. Moore | LW | LA | 10/30/2025 | Out of lineup | Personal | + |
| L. O'Conn | RW | COL | 10/30/2025 | Nearing return | hip | + |
| Z. Parekh | D | CGY | 10/30/2025 | Not playing | illness | + |
| C. Tanev | D | TOR | 10/31/2025 | Likely | concussion | + |
| P. Dubois | C | WSH | 10/31/2025 | Sustains lower-body injury | lower body | + |
| P. Dubois | C | WSH | 11/1/2025 | Deemed day-to-day | lower body | + |
| C. Tanev | D | TOR | 11/1/2025 | Taken out on stretcher | Upper body | + |
| E. Gudbra | D | CBJ | 11/1/2025 | Ruled out of weekend games | hip | + |
| D. Mateyc | D | CBJ | 11/2/2025 | Banged up following loss | Undisclosed | + |
| C. Tanev | D | TOR | 11/2/2025 | Discharged and headed home | Upper body | + |
| T. Foerst | RW | PHI | 11/2/2025 | Will miss next few games | lower body | + |
| M. Barron | LW | WIN | 11/3/2025 | Considered week-to-week | Undisclosed | + |
| J. Gadjov | LW | FLA | 11/3/2025 | Not going on road trip | Upper body | + |
| P. Dubois | C | WSH | 11/3/2025 | Set to miss extended time | lower body | + |
| J. Kulich | C | BUF | 11/3/2025 | Doubtful for Tuesday's game | Undisclosed | + |
| T. Dellan | C | SJ | 11/4/2025 | Dealing with lower-body issue | lower body | + |
| H. Mews | D | CGY | 11/4/2025 | Done for season | knee | + |
| D. Mateyc | D | CBJ | 11/4/2025 | Game-time call | Undisclosed | + |
| J. Kulich | C | BUF | 11/4/2025 | Unlikely to play | ear | + |
| E. Gudbra | D | CBJ | 11/4/2025 | Still sidelined | hip | + |
| P. Dubois | C | WSH | 11/4/2025 | Avoids season-ending injury | lower body | + |
| Z. MacEwe | C | NJ | 11/5/2025 | Not available | Upper body | + |
| T. Jarry | G | EDM | 11/5/2025 | Set for three-week absence | lower body | + |
| D. Mateyc | D | CBJ | 11/5/2025 | Officially ruled out | Undisclosed | + |
| J. Beeche | C | CGY | 11/6/2025 | Exits contest | Upper body | + |
| F. Hallan | C | PIT | 11/6/2025 | Not playing | Undisclosed | + |
| F. Hallan | C | PIT | 11/6/2025 | Injured at practice | Undisclosed | + |
| J. Benn | C | DAL | 11/6/2025 | Participates in optional skate | Upper body | + |
| T. Demko | G | VAN | 11/7/2025 | In doubt for back-to-back | Undisclosed | + |
| F. Nazar | C | CHI | 11/7/2025 | Departs Friday's game | Undisclosed | + |
| Z. Parekh | D | CGY | 11/7/2025 | Suffers upper-body injury | Upper body | + |
| F. Hallan | C | PIT | 11/7/2025 | Facing long-term absence | leg | + |
| J. Gadjov | LW | FLA | 11/8/2025 | Undergoes surgery | Upper body | + |
| D. Mateyc | D | CBJ | 11/8/2025 | Game-time call | Undisclosed | + |
| T. Demko | G | VAN | 11/8/2025 | Won't dress | Undisclosed | + |
| J. Beeche | C | CGY | 11/8/2025 | Won't play | Upper body | + |
| W. Karlss | C | VGK | 11/8/2025 | Suffers injury | Undisclosed | + |
| R. McDona | D | TB | 11/8/2025 | Leaves Saturday's game | Undisclosed | + |
| C. Tanev | D | TOR | 11/8/2025 | Returns to ice | Upper body | + |
| Z. Parekh | D | CGY | 11/8/2025 | Will miss time | Upper body | + |
| F. Nazar | C | CHI | 11/8/2025 | Deemed day-to-day | Undisclosed | + |
| Z. Parekh | D | CGY | 11/8/2025 | Out week-to-week | Upper body | + |
| C. Legaul | D | CAR | 11/9/2025 | Cut by skate, won't return to game | hand | + |
| J. Benn | C | DAL | 11/9/2025 | Joining team on upcoming road trip | Upper body | + |
| T. Demko | G | VAN | 11/9/2025 | Not available against Colorado | Undisclosed | + |
| P. Dubois | C | WSH | 11/9/2025 | Needs surgery | abdomen | + |
| W. Karlss | C | VGK | 11/9/2025 | Dealing with lower-body injury | lower body | + |
| F. Nazar | C | CHI | 11/9/2025 | Game-time decision | Undisclosed | + |
| F. Nazar | C | CHI | 11/9/2025 | Won't play | Undisclosed | + |
| C. Legaul | D | CAR | 11/9/2025 | Admitted to hospital | hand | + |
| W. Karlss | C | VGK | 11/10/2025 | Unavailable | lower body | + |
| M. Wood | LW | CBJ | 11/10/2025 | Under the weather | illness | + |
| J. Kulich | C | BUF | 11/10/2025 | Set to miss significant time | ear | + |
| J. Beeche | C | CGY | 11/11/2025 | Still out | Upper body | + |
| M. Barron | LW | WIN | 11/11/2025 | Labeled day-to-day | Undisclosed | + |
| T. Demko | G | VAN | 11/11/2025 | Departs Tuesday's game | Undisclosed | + |
| A. Stolar | G | TOR | 11/11/2025 | Hurt in first period | Upper body | + |
| V. Hedman | D | TB | 11/11/2025 | Dealing with undisclosed injury | Undisclosed | + |
| R. McDona | D | TB | 11/11/2025 | Set to miss time | Undisclosed | + |
| T. Foerst | RW | PHI | 11/11/2025 | Sporting regular sweater | lower body | + |
| L. O'Conn | RW | COL | 11/11/2025 | Still working way back from injury | hip | + |
| F. Nazar | C | CHI | 11/11/2025 | Set to miss out | Undisclosed | + |
| V. Hedman | D | TB | 11/12/2025 | Not playing | Undisclosed | + |
| J. Kivira | RW | COL | 11/12/2025 | Skating | lower body | + |
| H. Fleury | D | WIN | 11/12/2025 | Suffers undisclosed injury | Undisclosed | + |
| T. Demko | G | VAN | 11/12/2025 | Dealing with new lower-body issue | lower body | + |
| T. Demko | G | VAN | 11/12/2025 | Being evaluated | lower body | + |
| T. Foerst | RW | PHI | 11/12/2025 | Game-time call | lower body | + |
| A. Newhoo | C | MTL | 11/13/2025 | Sustains apparent lower-body injury | lower body | + |
| J. Beeche | C | CGY | 11/13/2025 | Remains out | Upper body | + |
| H. Fleury | D | WIN | 11/13/2025 | In concussion protocol | concussion | + |
| Z. MacEwe | C | NJ | 11/13/2025 | Exits Wednesday's contest | Undisclosed | + |
| W. Karlss | C | VGK | 11/13/2025 | Is week-to-week | lower body | + |
| A. Stolar | G | TOR | 11/13/2025 | Labeled day-to-day | Upper body | + |
| M. Rossi | C | VAN | 11/14/2025 | Considered week-to-week | lower body | + |
| A. Newhoo | C | MTL | 11/14/2025 | Undergoes surgery | ankle | + |
| F. Nazar | C | CHI | 11/14/2025 | Status uncertain | abdomen | + |
| M. Kessel | D | BUF | 11/15/2025 | Dealing with lower-body injury | lower body | + |
| M. Murray | G | SEA | 11/15/2025 | Injured late in first period | lower body | + |
| J. Benn | C | DAL | 11/15/2025 | Considered day-to-day | Upper body | + |
| F. Nazar | C | CHI | 11/15/2025 | Game-time decision | abdomen | + |
| V. Hedman | D | TB | 11/15/2025 | Won't return | Undisclosed | + |
| J. Beeche | C | CGY | 11/15/2025 | Not playing | Upper body | + |
| V. Hedman | D | TB | 11/16/2025 | Unavailable | Undisclosed | + |
| S. Honzek | LW | CGY | 11/16/2025 | Status now week-to-week | Upper body | + |
| C. Garlan | RW | VAN | 11/16/2025 | Injured in Tampa Bay | Undisclosed | + |
| K. Dach | C | MTL | 11/16/2025 | Will be out for a while. | foot | + |
| S. Honzek | LW | CGY | 11/16/2025 | Sustains upper-body injury | Upper body | + |
| F. Chytil | C | VAN | 11/16/2025 | Skating again and feeling better | Upper body | + |
| T. Demko | G | VAN | 11/16/2025 | Deemed week-to-week | lower body | + |
| T. Bluege | C | VAN | 11/16/2025 | Skating again | lower body | + |
| L. O'Conn | RW | COL | 11/17/2025 | Dealing with setback in recovery | hip | + |
| C. Schwin | RW | FLA | 11/17/2025 | Injured in Monday's victory | Undisclosed | + |
| C. Garlan | RW | VAN | 11/17/2025 | Unavailable | Undisclosed | + |
| M. Kessel | D | BUF | 11/17/2025 | Set for extended absence | lower body | + |
| Z. Bogosi | D | MIN | 11/18/2025 | Could return in late November | lower body | + |
| A. Romano | D | NYI | 11/18/2025 | Sustains injury late in game | Upper body | + |
| V. Hedman | D | TB | 11/18/2025 | Won't play | Undisclosed | + |
| C. Tanev | D | TOR | 11/18/2025 | Out at least one more week | Upper body | + |
| M. Murray | G | SEA | 11/18/2025 | Out for approximately six weeks | lower body | + |
| T. Bluege | C | VAN | 11/19/2025 | Suffers setback in recovery | lower body | + |
| N. Philp | C | CAR | 11/19/2025 | Sustains upper-body injury | Upper body | + |