| | | | | | |
| S. Mukham | D | SJ | 10/28/2025 | Classified as day-to-day | Upper body | + |
| C. Sisson | RW | VGK | 10/28/2025 | Not expected to play | Undisclosed | + |
| C. Sisson | RW | VGK | 10/28/2025 | Injured against Bolts | Undisclosed | + |
| C. Tanev | D | TOR | 10/27/2025 | Could return by end of week | Upper body | + |
| A. Romano | D | NYI | 10/27/2025 | Won't play | Upper body | + |
| W. Nyland | C | TOR | 10/27/2025 | Could return | lower body | + |
| R. Sandin | D | WSH | 10/27/2025 | Won't travel to Dallas | Upper body | + |
| J. Neighb | LW | STL | 10/27/2025 | Not playing | lower body | + |
| J. Gadjov | LW | FLA | 10/27/2025 | Out at least one week | Upper body | + |
| R. Thomas | C | STL | 10/27/2025 | Ruled out for Monday's game | Upper body | + |
| J. Bryson | D | BUF | 10/27/2025 | Could be available | concussion | + |
| W. Nyland | C | TOR | 10/25/2025 | Game-time call | Undisclosed | + |
| P. Laine | RW | MTL | 10/25/2025 | Out 3-4 months | abdomen | + |
| N. Hague | D | NSH | 10/25/2025 | Game-time decision | Upper body | + |
| W. Nyland | C | TOR | 10/25/2025 | Dealing with lower-body injury | lower body | + |
| R. Thomas | C | STL | 10/25/2025 | Sustains upper-body injury | Upper body | + |
| R. Sandin | D | WSH | 10/25/2025 | Remains out | Upper body | + |
| P. Dubois | C | WSH | 10/24/2025 | Not available | lower body | + |
| E. Robins | LW | CAR | 10/24/2025 | Poised for absence | Upper body | + |
| W. Nyland | C | TOR | 10/24/2025 | Leaves game late | Undisclosed | + |
| A. Kerfoo | C | UTA | 10/24/2025 | Undergoes core muscle surgery | abdomen | + |
| D. Forbor | D | VAN | 10/24/2025 | Considered week-to-week | Undisclosed | + |
| U. Luukko | G | BUF | 10/23/2025 | Back from assignment | lower body | + |
| R. Sandin | D | WSH | 10/23/2025 | Managing upper-body injury | Upper body | + |
| R. Sandin | D | WSH | 10/23/2025 | Won't play | Upper body | + |
| E. Robins | LW | CAR | 10/23/2025 | Departs from game | Upper body | + |
| A. Romano | D | NYI | 10/22/2025 | Not close to returning | Upper body | + |
| C. Tanev | D | TOR | 10/22/2025 | Questionable for Friday's game | Upper body | + |
| P. Engval | LW | NYI | 10/22/2025 | Likely out for season | ankle | + |
| B. Howden | C | VGK | 10/22/2025 | Trending toward playing | lower body | + |
| P. Laine | RW | MTL | 10/22/2025 | Seeking second opinion | lower body | + |
| A. Romano | D | NYI | 10/21/2025 | Unavailable against San Jose | Upper body | + |
| C. Tanev | D | TOR | 10/21/2025 | Sustains upper-body injury | Upper body | + |
| L. O'Conn | RW | COL | 10/21/2025 | Still three weeks out from return | hip | + |
| B. Boeser | RW | VAN | 10/21/2025 | Not expected to play | Personal | + |
| S. Gostis | D | CAR | 10/21/2025 | Out for remainder of trip | lower body | + |
| S. Noesen | C | NJ | 10/20/2025 | Nearing return to lineup | groin | + |
| A. Romano | D | NYI | 10/20/2025 | Game-time call | Upper body | + |
| P. Dubois | C | WSH | 10/20/2025 | Won't return | lower body | + |
| O. Sundqv | C | STL | 10/20/2025 | Full participant | lower body | + |
| P. Laine | RW | MTL | 10/20/2025 | Won't play | lower body | + |
| M. Rossi | C | VAN | 10/20/2025 | Not playing | lower body | + |
| Z. Bogosi | D | MIN | 10/20/2025 | Still sidelined against Rangers | lower body | + |
| B. Boeser | RW | VAN | 10/20/2025 | Possible | Personal | + |
| S. Gostis | D | CAR | 10/20/2025 | Sidelined against Vegas | lower body | + |
| B. Howden | C | VGK | 10/20/2025 | Will remain sidelined | lower body | + |
| B. Boeser | RW | VAN | 10/19/2025 | Unavailable due to personal reasons | Personal | + |
| O. Sundqv | C | STL | 10/18/2025 | Ruled out | lower body | + |
| A. Romano | D | NYI | 10/18/2025 | Not playing | Upper body | + |
| A. Romano | D | NYI | 10/18/2025 | Game-time decision | Undisclosed | + |
| P. Dubois | C | WSH | 10/18/2025 | Unavailable | lower body | + |
| P. Laine | RW | MTL | 10/18/2025 | Out of action | lower body | + |
| S. Gostis | D | CAR | 10/18/2025 | Suffers injury | lower body | + |
| S. Mukham | D | SJ | 10/18/2025 | Questionable for road trip | Upper body | + |
| Z. Bogosi | D | MIN | 10/18/2025 | Won't play | lower body | + |
| J. Bryson | D | BUF | 10/18/2025 | Suffers injury | Upper body | + |
| J. Bryson | D | BUF | 10/18/2025 | In concussion protocol | concussion | + |
| B. Howden | C | VGK | 10/18/2025 | Won't play | lower body | + |
| J. Danfor | RW | BUF | 10/17/2025 | Out more than a month | lower body | + |
| P. Dubois | C | WSH | 10/17/2025 | Won't play | lower body | + |
| S. Mukham | D | SJ | 10/17/2025 | Likely out through weekend | Undisclosed | + |
| Z. Bogosi | D | MIN | 10/17/2025 | Injured in Friday's game | Undisclosed | + |
| A. Kopita | C | LA | 10/17/2025 | Deemed week-to-week | foot | + |
| T. Terry | RW | ANA | 10/16/2025 | Expected to play | Personal | + |
| A. Kopita | C | LA | 10/16/2025 | Game-time call | Undisclosed | + |
| T. Terry | RW | ANA | 10/16/2025 | Not at practice | Personal | + |
| A. Kopita | C | LA | 10/16/2025 | Won't play | lower body | + |
| B. Howden | C | VGK | 10/16/2025 | Ruled out for Thursday's game | lower body | + |
| D. Kuliko | D | FLA | 10/15/2025 | Will miss approximately five months | Upper body | + |
| J. Danfor | RW | BUF | 10/15/2025 | Exits Wednesday's game | lower body | + |
| D. Forbor | D | VAN | 10/15/2025 | Placed on injured reserve | Undisclosed | + |
| A. Kopita | C | LA | 10/15/2025 | Misses practice | Undisclosed | + |
| O. Sundqv | C | STL | 10/14/2025 | Remains out | lower body | + |
| P. Dubois | C | WSH | 10/14/2025 | Not playing | lower body | + |
| B. Howden | C | VGK | 10/14/2025 | Absence due to LBI | lower body | + |
| Z. MacEwe | C | NJ | 10/13/2025 | Out indefinitely | Undisclosed | + |
| H. Fleury | D | WIN | 10/13/2025 | Won't play | Kneecap | + |
| J. Norris | C | BUF | 10/13/2025 | Poised for eight-week absence | Upper body | + |
| H. Fleury | D | WIN | 10/12/2025 | Officially day-to-day | Kneecap | + |
| P. Dubois | C | WSH | 10/12/2025 | Exits Sunday's game in Manhattan | Undisclosed | + |
| P. Kochet | G | CAR | 10/11/2025 | Out for at least one week | lower body | + |
| J. Norris | C | BUF | 10/11/2025 | Out indefinitely | Upper body | + |
| H. Fleury | D | WIN | 10/11/2025 | Suffers injury | Kneecap | + |
| J. Norris | C | BUF | 10/10/2025 | Set to miss out | Upper body | + |
| P. Kochet | G | CAR | 10/9/2025 | Not in lineup | Undisclosed | + |
| J. Brodin | D | MIN | 10/9/2025 | Won't play | Upper body | + |
| J. Norris | C | BUF | 10/9/2025 | Hurt late in Thursday's game | Upper body | + |
| D. Kuliko | D | FLA | 10/9/2025 | Exits with injury | Upper body | + |
| C. Ritchi | C | NYI | 10/8/2025 | Resumes skating | lower body | + |
| P. Kochet | G | CAR | 10/8/2025 | Misses practice | Undisclosed | + |
| J. Brodin | D | MIN | 10/8/2025 | Might be available | Upper body | + |
| O. Sundqv | C | STL | 10/7/2025 | Labeled week-to-week | lower body | + |
| U. Luukko | G | BUF | 10/6/2025 | Officially ruled out | lower body | + |
| J. Brodin | D | MIN | 10/6/2025 | Remains unavailable | Upper body | + |
| C. Ritchi | C | NYI | 10/6/2025 | Placed on non-roster list | lower body | + |
| A. Thornt | G | UTA | 10/6/2025 | Dealing with undisclosed injury | Undisclosed | + |
| J. MacDon | D | COL | 10/6/2025 | Lands on injured, non-roster list | hip | + |
| J. Brodin | D | MIN | 10/6/2025 | Put on injured reserve | Upper body | + |
| O. Sundqv | C | STL | 10/5/2025 | Hurt during practice | lower body | + |
| V. Hedman | D | TB | 10/4/2025 | Unavailable | Undisclosed | + |
| U. Luukko | G | BUF | 10/3/2025 | Set to miss at least one week | lower body | + |
| L. Cooley | C | UTA | 10/3/2025 | Wearing regular jersey at practice | Undisclosed | + |
| U. Luukko | G | BUF | 10/3/2025 | Won't dress | lower body | + |
| C. Ritchi | C | NYI | 10/3/2025 | Set to miss 1-2 weeks | lower body | + |
| S. Noesen | C | NJ | 10/3/2025 | Practicing in regular jersey | groin | + |
| L. Cooley | C | UTA | 10/3/2025 | Ready for regular season | Undisclosed | + |
| S. Noesen | C | NJ | 10/3/2025 | Not close to playing | groin | + |
| J. Ivany | D | PIT | 10/2/2025 | Set for six-week absence | lower body | + |
| J. Ivany | D | PIT | 10/2/2025 | Won't practice | lower body | + |
| C. Ritchi | C | NYI | 10/2/2025 | Hurt in Thursday's game | lower body | + |
| V. Hedman | D | TB | 10/2/2025 | Ruled out for Thursday's game | Undisclosed | + |
| J. Neighb | LW | STL | 10/1/2025 | Dealing with soreness | Undisclosed | + |
| U. Luukko | G | BUF | 10/1/2025 | Injured again | lower body | + |
| J. Neighb | LW | STL | 10/1/2025 | Won't play | Undisclosed | + |
| J. Ivany | D | PIT | 10/1/2025 | Leaves Wednesday's contest | lower body | + |
| N. Philp | C | CAR | 9/30/2025 | Battling illness | illness | + |
| S. Edvins | D | DET | 9/30/2025 | Cleared for contact | lower body | + |
| T. Demko | G | VAN | 9/30/2025 | Away from team for personal reasons | Personal | + |
| S. Edvins | D | DET | 9/29/2025 | Should play Opening Night | lower body | + |
| P. Kochet | G | CAR | 9/29/2025 | Back skating | Undisclosed | + |
| L. Cooley | C | UTA | 9/29/2025 | Ruled out for Tuesday's game | Undisclosed | + |
| V. Hedman | D | TB | 9/29/2025 | Won't play | Undisclosed | + |
| J. Brodin | D | MIN | 9/28/2025 | Practices fully | Upper body | + |
| V. Hedman | D | TB | 9/27/2025 | Sitting out | Undisclosed | + |
| J. Kulich | C | BUF | 9/27/2025 | Unavailable | Undisclosed | + |
| G. Briseb | D | VAN | 9/27/2025 | Undergoes surgery | lower body | + |
| A. Barkov | C | FLA | 9/26/2025 | Undergoing right knee surgery | knee | + |
| P. Kochet | G | CAR | 9/26/2025 | Won't suit up against Bolts | Undisclosed | + |
| A. Barkov | C | FLA | 9/26/2025 | Missing 7-9 months | knee | + |
| V. Hedman | D | TB | 9/26/2025 | Makes precautionary exit | Undisclosed | + |
| M. McLaug | C | NJ | 9/26/2025 | Out for rest of camp | Undisclosed | + |
| J. Kulich | C | BUF | 9/25/2025 | Tweaks a muscle | Undisclosed | + |
| U. Luukko | G | BUF | 9/25/2025 | Back at practice | lower body | + |
| J. Gadjov | LW | FLA | 9/25/2025 | On the sidelines | lower body | + |
| L. Cooley | C | UTA | 9/25/2025 | Won't play | Undisclosed | + |
| A. Barkov | C | FLA | 9/25/2025 | Sustains apparent right leg injury | leg | + |
| P. Kochet | G | CAR | 9/25/2025 | Dealing with minor injury | Undisclosed | + |
| U. Luukko | G | BUF | 9/25/2025 | Anticipating Opening Night return | lower body | + |
| A. Barkov | C | FLA | 9/25/2025 | Seeing doctors | leg | + |
| N. Hague | D | NSH | 9/24/2025 | Set to miss 4-6 weeks | Upper body | + |
| T. Foerst | RW | PHI | 9/23/2025 | Ditches non-contact sweater | elbow | + |
| N. Hague | D | NSH | 9/23/2025 | Not suiting up | Undisclosed | + |
| Z. Buium | D | VAN | 9/23/2025 | Won't play versus Stars | Upper body | + |
| L. Cooley | C | UTA | 9/22/2025 | Departs Sunday's game | Undisclosed | + |
| L. Cooley | C | UTA | 9/22/2025 | Labeled day-to-day | Undisclosed | + |
| N. Hague | D | NSH | 9/21/2025 | Hurt after taking hit | Undisclosed | + |
| U. Luukko | G | BUF | 9/20/2025 | Improving, not practicing yet | lower body | + |
| A. Kerfoo | C | UTA | 9/19/2025 | Week-to-week with lower-body injury | lower body | + |
| Z. Buium | D | VAN | 9/19/2025 | Dealing with upper-body injury | Upper body | + |
| J. Neighb | LW | STL | 9/18/2025 | Absent to begin training camp | Personal | + |
| P. Engval | LW | NYI | 9/18/2025 | Out 2-3 weeks | hip | + |
| L. Hughes | D | NJ | 9/18/2025 | Remains unsigned | Contract Dispute | + |
| S. Varlam | G | NYI | 9/18/2025 | Skating, no timeline for return | knee | + |
| S. Noesen | C | NJ | 9/18/2025 | Out with groin injury | groin | + |
| M. McTavi | C | ANA | 9/18/2025 | Absent from camp | Contract Dispute | + |
| L. O'Conn | RW | COL | 9/17/2025 | On track for November return | hip | + |
| S. Edvins | D | DET | 9/17/2025 | Sustains lower-body injury | lower body | + |
| T. Nosek | LW | FLA | 9/17/2025 | Set to miss several months | knee | + |
| T. Foerst | RW | PHI | 9/16/2025 | Not cleared for contact yet | elbow | + |
| S. Varlam | G | NYI | 9/15/2025 | Status uncertain for start of camp | knee | + |
| U. Luukko | G | BUF | 9/12/2025 | Suffers offseason injury | Undisclosed | + |
| S. Mukham | D | SJ | 9/9/2025 | On ice | shoulder | + |
| J. MacDon | D | COL | 9/4/2025 | Undergoes hip surgery | hip | + |